dopamine key to mystery of metabolic dysfunction & anti-psychotic drugs

Anti-psychotic drugs do not only block dopamine signaling in the brain, they also block dopamine signaling in the pancreas. Blocking dopamine signaling in the pancreas leads to uncontrolled production of blood-glucose regulating hormones, increasing obesity and diabetes risks. Why do patients who receive antipsychotic medications to manage schizophrenia and bipolar disorder quickly gain weight and …